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BAY-5094

BAY-5094 is a PPAR gamma (PPARG) inverse agonist. BAY-5094 has oral activity. BAY-5094 can be used in the research of luminal bladder cancer[1].

Product Specifications

CAS Number

2891706-78-6

UNSPSC

12352005

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bay-5094.html

Purity

98.04

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(C(NCC2=CC=C(C(F)=C2)F)=O)=C(C=C1Cl)F)NC3=CC=C(C(C)(C)O)C=C3

Molecular Formula

C24H20ClF3N2O3

Molecular Weight

476.88

References & Citations

[1]Douglas L Orsi, et al. Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists. Bioorg Med Chem. 2023.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PPARγ

Available Sizes

Frequently Asked Questions

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