Decanoic acid-d3

Decanoic acid-d3 is the deuterium labeled Decanoic acid. Decanoic acid, a component of medium chain triclycerides, is a brain-penetrant and non-competitive inhibitor of AMPA receptor. Decanoic acid has antiseizure effects[1][2][3].

Product Specifications

CAS Number

[102611-15-4]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

IGluR

Type

Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Purity

99.0

Solubility

DMF : ≥ 25mg/mL|DMSO : ≥ 10mg/mL|Ethanol : ≥ 25mg/mL

Smiles

[2H]C([2H])([2H])CCCCCCCCC(O)=O

Molecular Formula

C10H17D3O2

Molecular Weight

175.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Chang P, et al. Seizure control by decanoic acid through direct AMPA receptor inhibition. Brain. 2016 Feb;139 (Pt 2) :431-43.|[3]Kim S, et, al. Selective production of decanoic acid from iterative reversal of β-oxidation pathway. Biotechnol Bioeng. 2018 May;115 (5) :1311-1320.|[4]Boison D, et, al. New insights into the mechanisms of the ketogenic diet. Curr Opin Neurol. 2017 Apr;30 (2) :187-192.