Datelliptium (chloride)
Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities.
Product Specifications
CAS Number
105118-14-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Datelliptium_chloride.html
Purity
98.33
Solubility
DMSO : < 1 mg/mL|H2O : 41.67 mg/mL (ultrasonic)
Smiles
CC1=C2C(NC3=C2C=C(O)C=C3)=C(C)C4=CC=[N+](CCN(CC)CC)C=C41.[Cl-]
Molecular Formula
C23H28ClN3O
Molecular Weight
397.94
Precautions
H302, H315, H319, H335
References & Citations
[1]Donato MT, et al. Toxicity of the antitumoral drug datelliptium in hepatic cells: Use of models in vitro for the prediction of toxicity in vivo. Toxicol In Vitro. 1992 Jul;6 (4) :295-302.|[2]Mucci-LoRusso P, et al. Activity of datelliptium acetate (NSC 311152; SR 95156A) against solid tumors of mice. Invest New Drugs. 1990 Aug;8 (3) :253-61.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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