Datelliptium (chloride)

Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities.

Product Specifications

CAS Number

[105118-14-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Datelliptium_chloride.html

Purity

98.33

Solubility

DMSO : < 1 mg/mL|H2O : 41.67 mg/mL (ultrasonic)

Smiles

CC1=C2C(NC3=C2C=C(O)C=C3)=C(C)C4=CC=[N+](CCN(CC)CC)C=C41.[Cl-]

Molecular Formula

C23H28ClN3O

Molecular Weight

397.94

Precautions

H302, H315, H319, H335

References & Citations

[1]Donato MT, et al. Toxicity of the antitumoral drug datelliptium in hepatic cells: Use of models in vitro for the prediction of toxicity in vivo. Toxicol In Vitro. 1992 Jul;6 (4) :295-302.|[2]Mucci-LoRusso P, et al. Activity of datelliptium acetate (NSC 311152; SR 95156A) against solid tumors of mice. Invest New Drugs. 1990 Aug;8 (3) :253-61.