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Diorcinol

Diorcinol is a potent SHP1 inhibitor with an IC50 value of 0.96 μM. Diorcinol can be isolated from Aspergillus sydowii. Diorcinol has good blood-brain barrier penetration and can be used for diabetes research[1].

Product Specifications

CAS Number

20282-75-1

UNSPSC

12352005

Target

Phosphatase; SHP1

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/diorcinol.html

Purity

99.30

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC1=CC(C)=CC(OC2=CC(O)=CC(C)=C2)=C1

Molecular Formula

C14H14O3

Molecular Weight

230.26

References & Citations

[1]Shi X, et al. Chemical Epigenetic Regulation Secondary Metabolites Derived from Aspergillus sydowii DL1045 with Inhibitory Activities for Protein Tyrosine Phosphatases. Molecules. 2024 Jan 31;29 (3) :670.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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