Diorcinol
Diorcinol is a potent SHP1 inhibitor with an IC50 value of 0.96 μM. Diorcinol can be isolated from Aspergillus sydowii. Diorcinol has good blood-brain barrier penetration and can be used for diabetes research[1].
Product Specifications
CAS Number
[20282-75-1]
UNSPSC
12352005
Target
Phosphatase; SHP1
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/diorcinol.html
Purity
99.30
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC1=CC(C)=CC(OC2=CC(O)=CC(C)=C2)=C1
Molecular Formula
C14H14O3
Molecular Weight
230.26
References & Citations
[1]Shi X, et al. Chemical Epigenetic Regulation Secondary Metabolites Derived from Aspergillus sydowii DL1045 with Inhibitory Activities for Protein Tyrosine Phosphatases. Molecules. 2024 Jan 31;29 (3) :670.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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