Guanosine 5'-triphosphate (trisodium salt)
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration[1][2].
Product Specifications
CAS Number
36051-31-7
Product Name Alternative
5'-GTP (trisodium salt)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis; Endogenous Metabolite
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5_acute_-GTP-trisodium-salt.html
Purity
99.76
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
O=P(OP(OP(O)(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2NC(N)=NC3=O)O1)=O)([O])=O)(O[Na])O[Na].[Na]
Molecular Formula
C10H13N5Na3O14P3
Molecular Weight
589.13
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Citation 01
Anal Chim Acta. 2021 Dec 15:1188:339180.|Mol Cell. 2022 Jun 2;82 (11) :2032-2049.e7.|Bioorg Med Chem. 2021 Jan 1;29:115899.|bioRxiv. 2024 Apr 24.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD50 (ICAM-3) (186-2G9), CF405S conjugate, 0.1mg/mL
Human IgG Immunoglobulin (IG266), CF568 conjugate, 0.1mg/mL
