Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

(S, R, S) -AHPC-PEG3-NH2 (hydrochloride)

(S, R, S) -AHPC-PEG3-NH2 (VH032-PEG3-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S, R, S) -AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.

Product Specifications

CAS Number

2097971-11-2

Product Name Alternative

VH032-PEG3-NH2 (hydrochloride) ; VHL Ligand-Linker Conjugates 1 (hydrochloride) ; E3 ligase Ligand-Linker Conjugates 5

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/E3_ligase_Ligand-Linker_Conjugates_5.html

Purity

99.01

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C([C@H]1N(C([C@H](C(C)(C)C)NC(COCCOCCOCCN)=O)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.[H]Cl

Molecular Formula

C30H46ClN5O7S

Molecular Weight

656.23

Precautions

H302, H315, H319, H335

References & Citations

[1]Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018 Jan 25;61 (2) :504-513.

Shipping Conditions

Dry Ice

Storage Conditions

-80°C, protect from light, stored under nitrogen

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Von Hippel-Lindau (VHL)

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

RPL22L1 (NM_001099645) Human Over-expression Lysate
LC420471 20 µg

RPL22L1 (NM_001099645) Human Over-expression Lysate

Sign In for Pricing
View Details
PAI1 (SERPINE1) Rabbit Monoclonal Antibody [Clone ID: R07-2C3]
TA385228 100 µL

PAI1 (SERPINE1) Rabbit Monoclonal Antibody [Clone ID: R07-2C3]

Sign In for Pricing
View Details
Ang5 Mouse Gene Knockout Kit (CRISPR)
KN501232 1 Kit

Ang5 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
1-(5-O-Acetyl-b-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one
TRC-A188035-25MG 25 mg

1-(5-O-Acetyl-b-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one

Sign In for Pricing
View Details
Cyclin A2 (E67), CF405S conjugate, 0.1mg/mL
BNC040673-500 1x 500 µL

Cyclin A2 (E67), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
TentaGel® HL SH
HL12904.0.5G 5 g

TentaGel® HL SH

Sign In for Pricing
View Details