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DS12881479

DS12881479 is a potent and selective Mnk1 inhibitor with an IC50 value of 21 nM. DS12881479 can be used in cancer research[1].

Product Specifications

CAS Number

[2373065-59-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

MNK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ds12881479.html

Purity

99.63

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(C1CCN(C)CC1)NC2=NC=C(C3=CC=CC=C3)S2

Molecular Formula

C16H19N3OS

Molecular Weight

301.41

Precautions

H302, H315, H319

References & Citations

[1]Yumi Matsui, et al. A novel inhibitor stabilizes the inactive conformation of MAPK-interacting kinase 1. Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74 (Pt 3) :156-160.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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