DS12881479

DS12881479 is a potent and selective Mnk1 inhibitor with an IC50 value of 21 nM. DS12881479 can be used in cancer research[1].

Product Specifications

CAS Number

[2373065-59-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

MNK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ds12881479.html

Purity

99.63

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(C1CCN(C)CC1)NC2=NC=C(C3=CC=CC=C3)S2

Molecular Formula

C16H19N3OS

Molecular Weight

301.41

Precautions

H302, H315, H319

References & Citations

[1]Yumi Matsui, et al. A novel inhibitor stabilizes the inactive conformation of MAPK-interacting kinase 1. Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74 (Pt 3) :156-160.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

AMM12771VCF 100 µg

PFDN3 (VBP1) Mouse Monoclonal Antibody [Clone ID: LBI2A3]

Ask

View Details

NBP2-74866B 0.1 mL

Mouse Monoclonal WDR61 Antibody (OTI4C4) [Biotin]

Ask

View Details

DF14222-BP 1 mg

HOXA13 Peptide

Ask

View Details

42275101 1 µg

RPS24P3 AAV Vector (Human) (CMV)

Ask

View Details

P509319 100 µg

TSG101 Protein (N-His, Human)

Ask

View Details