DS12881479
Product Specifications
UNSPSC Description
DS12881479 is a potent and selective Mnk1 inhibitor with an IC50 value of 21 nM. DS12881479 can be used in cancer research[1].
Target Antigen
MNK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ds12881479.html
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(C1CCN(C)CC1)NC2=NC=C(C3=CC=CC=C3)S2
Molecular Weight
301.41
References & Citations
[1]Yumi Matsui, et al. A novel inhibitor stabilizes the inactive conformation of MAPK-interacting kinase 1. Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74(Pt 3):156-160.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148105/DS12881479-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148105/DS12881479-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2373065-59-7
Available Sizes
Curated Selection
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