DS12881479
DS12881479 is a potent and selective Mnk1 inhibitor with an IC50 value of 21 nM. DS12881479 can be used in cancer research[1].
Product Specifications
CAS Number
[2373065-59-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
MNK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ds12881479.html
Purity
99.63
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(C1CCN(C)CC1)NC2=NC=C(C3=CC=CC=C3)S2
Molecular Formula
C16H19N3OS
Molecular Weight
301.41
Precautions
H302, H315, H319
References & Citations
[1]Yumi Matsui, et al. A novel inhibitor stabilizes the inactive conformation of MAPK-interacting kinase 1. Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74 (Pt 3) :156-160.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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