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(S,R,S)-AHPC-C4-NH2 (hydrochloride)

Product Specifications

UNSPSC Description

(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].

Target Antigen

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Protac_linker_5.html

Purity

99.29

Solubility

DMSO : ≥ 109.6 mg/mL|H2O : ≥ 50 mg/mL

Smiles

O=C(N[C@@H](C(C)(C)C)C(N1C[C@H](O)C[C@H]1C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)=O)CCCCN.[H]Cl

Molecular Weight

566.16

References & Citations

[1]Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-114176/S-R-S-AHPC-C4-NH2-hydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-114176/S-R-S-AHPC-C4-NH2-hydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2245697-83-8

Available Sizes

Curated Selection

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