Isosakuranetin
Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a TRPM3 blocker[1][2][3].
Product Specifications
CAS Number
[480-43-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
TRP Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Isosakuranetin.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C1C[C@@H](C2=CC=C(OC)C=C2)OC3=CC(O)=CC(O)=C13
Molecular Formula
C16H14O5
Molecular Weight
286.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Drira R, et al. Isosakuranetin, a 4'-O-methylated flavonoid, stimulates melanogenesis in B16BL6 murine melanoma cells. Life Sci. 2015 Dec 15;143:43-9.|[2]Jia S, et al. Antinociceptive Effects of Isosakuranetin in a Rat Model of Peripheral Neuropathy. Pharmacology. 2017;100 (3-4) :201-207.|[3]Straub I, et al. Flavanones that selectively inhibit TRPM3 attenuate thermal nociception in vivo. Mol Pharmacol. 2013 Nov;84 (5) :736-50.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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