XL041

XL041 (BMS-852927) is an LXRβ-selective agonist.

Product Specifications

CAS Number

[1256918-39-4]

Product Name Alternative

BMS-852927

UNSPSC

12352005

Target

LXR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/BMS-852927.html

Concentration

10mM

Purity

99.44

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(C)(C)C1=CN(C2=CC=C(C3=CC(S(=O)(C)=O)=C(CO)C(F)=C3)C=C2F)C(C(C)(C4=C(Cl)C=CC=C4Cl)C)=N1

Molecular Formula

C29H28Cl2F2N2O4S

Molecular Weight

609.51

References & Citations

[1]Kirchgessner TG, et al. Beneficial and Adverse Effects of an LXR Agonist on Human Lipid and Lipoprotein Metabolism and Circulating Neutrophils. Cell Metab. 2016 Aug 9;24 (2) :223-33.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Curated Selection

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