DC661
Product Specifications
UNSPSC Description
DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor, inhibits autophagy, and acts as an anti-lysosomal agent. Anti-cancer activity[1].
Target Antigen
Apoptosis; Autophagy
Type
Reference compound
Related Pathways
Apoptosis;Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/DC661.html
Purity
99.53
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
CN(CCCCCCNC1=CC=NC2=CC(Cl)=CC=C12)CCCCCCNC3=CC=NC4=CC(Cl)=CC=C34
Molecular Weight
552.58
References & Citations
[1]Rebecca VW, et al. PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer. ancer Discov. 2019 Feb;9(2):220-229.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111621/DC661-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111621/DC661-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1872387-43-3
Available Sizes
Curated Selection
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