8 (S),9 (R) -EET
8 (S),9 (R) -EET is an eicosanoid product of Arachidonic acid (AA; HY-109590) by cytochromes P450. 8 (S),9 (R) -EET dilates canine epicardial arterioles in a concentration-dependent manner with an EC50 value of 121 nM[1][2].
Product Specifications
CAS Number
123931-39-5
UNSPSC
12352005
Target
Drug Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/8-s-9-r-eet.html
Smiles
CCCCC/C=C\C/C=C\C[C@@H]1[C@@H](O1)C/C=C\CCCC(O)=O
Molecular Formula
C20H32O3
Molecular Weight
320.47
References & Citations
[1]D C Zeldin, et al. Epoxygenase pathways of arachidonic acid metabolism. J Biol Chem. 2001 Sep 28;276 (39) :36059-62.|[2]Y Zhang, et al. EET homologs potently dilate coronary microvessels and activate BK (Ca) channels. Am J Physiol Heart Circ Physiol. 2001 Jun;280 (6) :H2430-40.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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