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Aurora kinase inhibitor-8

Aurora kinase inhibitor-8 is a highly selective inhibitor of the Aurora kinases.

Product Specifications

CAS Number

2133001-88-2

UNSPSC

12352005

Target

Aurora Kinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aurora-kinase-inhibitor-8.html

Purity

98.01

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=C(NC2=NC=C(N3C)C(N(C)C4=CC=C(C)C=C4C3=O)=N2)C=C1)C5=CC=C(NC(CC)=O)C=C5

Molecular Formula

C30H29N7O3

Molecular Weight

535.60

References & Citations

[1]Ferguson FM, et al. Characterization of a highly selective inhibitor of the Aurora kinases. Bioorg Med Chem Lett. 2017 Sep 15;27 (18) :4405-4408.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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