Aurora kinase inhibitor-8
Aurora kinase inhibitor-8 is a highly selective inhibitor of the Aurora kinases.
Product Specifications
CAS Number
2133001-88-2
UNSPSC
12352005
Target
Aurora Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aurora-kinase-inhibitor-8.html
Purity
98.01
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(NC2=NC=C(N3C)C(N(C)C4=CC=C(C)C=C4C3=O)=N2)C=C1)C5=CC=C(NC(CC)=O)C=C5
Molecular Formula
C30H29N7O3
Molecular Weight
535.60
References & Citations
[1]Ferguson FM, et al. Characterization of a highly selective inhibitor of the Aurora kinases. Bioorg Med Chem Lett. 2017 Sep 15;27 (18) :4405-4408.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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