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Aurora kinase inhibitor-8

Product Specifications

UNSPSC Description

Aurora kinase inhibitor-8 is a highly selective inhibitor of the Aurora kinases.

Target Antigen

Aurora Kinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Epigenetics

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aurora-kinase-inhibitor-8.html

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=C(NC2=NC=C(N3C)C(N(C)C4=CC=C(C)C=C4C3=O)=N2)C=C1)C5=CC=C(NC(CC)=O)C=C5

Molecular Weight

535.60

References & Citations

[1]Ferguson FM, et al. Characterization of a highly selective inhibitor of the Aurora kinases. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4405-4408.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-144991/Aurora-kinase-inhibitor-8-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-144991/Aurora-kinase-inhibitor-8-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2133001-88-2

Available Sizes

Curated Selection

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