N- (3-Aminopropyl) cyclohexylamine

N- (3-Aminopropyl) cyclohexylamine, a cyclohexylamine derivative, acts as a selective and competitive inhibitor of spermine synthase. N- (3-Aminopropyl) cyclohexylamine can be used for the research of neurological diseases[1].

Product Specifications

CAS Number

[3312-60-5]

UNSPSC

12352211

Hazard Statement

H314

Target

JAK

Type

Reference compound

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/n-3-aminopropyl-cyclohexylamine.html

Purity

99.37

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

NCCCNC1CCCCC1

Molecular Formula

C9H20N2

Molecular Weight

156.27

Precautions

H314

References & Citations

[1]P J Chu, et al.Antagonistic effect of N- (3-Aminopropyl) cyclohexylamine on neurotrophic action of spermine in primary cultured rat hippocampal and cerebellar neurons. Jpn J Pharmacol. 1995 Dec;69 (4) :311-5.|[2]Kovács Z, et al., Critical Role of Astrocytic Polyamine and GABA Metabolism in Epileptogenesis. Front Cell Neurosci. 2022 Jan 6;15:787319.|[3]Ohtani M, et al., Spermidine regulates insulin synthesis and cytoplasmic Ca (2+) in mouse beta-TC6 insulinoma cells. Cell Struct Funct. 2009;34 (2) :105-13.|[4]Ishii I, et al., Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells. Amino Acids. 2012 Feb;42 (2-3) :619-26.