F-SAHA

F-SAHA is a HDAC inhibitor (HDACi) and its 18F labeled derivative can be used in tumor imaging research[1].

Product Specifications

CAS Number

[149648-08-8]

Product Name Alternative

P-Fluoro-SAHA

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/f-saha.html

Concentration

10mM

Purity

99.90

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

O=C(CCCCCCC(NC1=CC=C(C=C1)F)=O)NO

Molecular Formula

C14H19FN2O3

Molecular Weight

282.31

References & Citations

[1]Hendricks JA, et al. In vivo PET imaging of histone deacetylases by 18F-suberoylanilide hydroxamic acid (18F-SAHA) . J Med Chem. 2011 Aug 11;54 (15) :5576-82.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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