STAT6-IN-2
STAT6-IN-2 (Compound R-84) is a STAT6 inhibitor that can inhibit the tyrosine phosphorylation of STAT6. STAT6-IN-2 can also inhibit the secretion of eotaxin-3. STAT6-IN-2 can be used in the research of immune diseases and allergic inflammatory diseases such as asthma[1].
Product Specifications
CAS Number
1355594-85-2
UNSPSC
12352005
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/stat6-in-2.html
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN1C(C2=CC(C(NCCC3=CC=CC=N3)=O)=NC(C(N[C@H](C)C(C)C)=O)=C2)=CC4=CC=CC=C41
Molecular Formula
C28H31N5O2
Molecular Weight
469.58
References & Citations
[1]Zhou L, et.al. STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells. Bioorg Med Chem. 2012 Jan 15;20 (2) :750-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940158-100 1x 100 µL
Cytokeratin 17 (E3), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
![GLI2 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1G2]](https://cdn.genprice.uk/products/937/68dd1b7b061270361ea1c331/imageurl/ta804599bm.webp)
TA804599BM 100 µL
GLI2 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1G2]
Sign In for Pricing
View Details