Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

MIV-247

MIV-247 is a selective cathepsin S inhibitor with Kis of 2.1, 4.2 and 7.5 nM for human, mouse and cynomolgus monkey cathepsin S, respectively.

Product Specifications

CAS Number

1352817-76-5

UNSPSC

12352211

Target

Cathepsin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/MIV-247.html

Solubility

10 mM in DMSO

Smiles

FC1(CCCC1)C[C@H](NC(C(F)(F)C)=O)C(NC2(CCC2)C(C(N)=O)=O)=O

Molecular Formula

C17H24F3N3O4

Molecular Weight

391.39

References & Citations

[1]Hewitt E. et al. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain. J Pharmacol Exp Ther. 2016 Sep;358 (3) :387-96.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cathepsin S

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Human ANKRD13C activation kit by CRISPRa
GA113075 1 Kit

Human ANKRD13C activation kit by CRISPRa

Sign In for Pricing
View Details
Renalase (Renal Cell Marker) (RNLS/1940), Biotin conjugate, 0.1mg/mL
BNCB1940-500 1x 500 µL

Renalase (Renal Cell Marker) (RNLS/1940), Biotin conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Caspase-2 Antibody
F42862-0.08ML 0.08 mL

Caspase-2 Antibody

Sign In for Pricing
View Details
Recombinant EIF1AX Antibody
RC-4569-01 50 μL

Recombinant EIF1AX Antibody

Sign In for Pricing
View Details
Recombinant EIF1AX Antibody
RC-4569-02 100 µL

Recombinant EIF1AX Antibody

Sign In for Pricing
View Details
Recombinant EIF1AX Antibody
RC-4569-03 1 mL

Recombinant EIF1AX Antibody

Sign In for Pricing
View Details