7-Ethoxycoumarin

7-Ethoxycoumarin is a substrate of cytochrome P450 (CYP450) . 7-Ethoxycoumarin has been used for the functional characterization of various CYPs and for the generation of 7-hydroxycoumarin (HY-N0573) [1].

Product Specifications

CAS Number

[31005-02-4]

Product Name Alternative

7-O-Ethylumbelliferone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Cytochrome P450

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/7-ethoxycoumarin.html

Purity

99.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C=CC2=CC=C(OCC)C=C2O1

Molecular Formula

C11H10O3

Molecular Weight

190.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Kim DH, et al. Generation of human metabolites of 7-ethoxycoumarin by bacterial cytochrome P450 BM3. Drug Metab Dispos. 2008 Nov;36 (11) :2166-70.|[2]Steensma A, et al. Metabolism of coumarin and 7-ethoxycoumarin by rat, mouse, guinea pig, cynomolgus monkey and human precision-cut liver slices. Xenobiotica. 1994 Sep;24 (9) :893-907.|[3]Coomes MW, et al. Oxidation of 7-ethoxycoumarin and conjugation of umbelliferone by intact, viable epidermal cells from the hairless mouse. J Invest Dermatol. 1984 Jun;82 (6) :598-601.