Boc-Gln-Ala-Arg-AMC (acetate)
Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2[1][2].
Product Specifications
UNSPSC
12171500
Target
Ser/Thr Protease
Type
Dye Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/boc-gln-ala-arg-amc-acetate.html
Purity
99.69
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
C[C@@H](C(N[C@@H](CCCNC(N)=N)C(NC1=CC=C(C(C)=CC(O2)=O)C2=C1)=O)=O)NC([C@H](CCC(N)=O)NC(OC(C)(C)C)=O)=O.CC(O)=O
Molecular Formula
C31H46N8O10
Molecular Weight
690.74
References & Citations
[1]Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20 (2) :288-292. |[2]Ko CJ, et al. Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis. Oncogene. 2020 Sep;39 (37) :5950-5963.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
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