Boc-Gln-Ala-Arg-AMC (acetate)

Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2[1][2].

Product Specifications

UNSPSC

12171500

Target

Ser/Thr Protease

Type

Dye Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/boc-gln-ala-arg-amc-acetate.html

Purity

99.69

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

C[C@@H](C(N[C@@H](CCCNC(N)=N)C(NC1=CC=C(C(C)=CC(O2)=O)C2=C1)=O)=O)NC([C@H](CCC(N)=O)NC(OC(C)(C)C)=O)=O.CC(O)=O

Molecular Formula

C31H46N8O10

Molecular Weight

690.74

References & Citations

[1]Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20 (2) :288-292. |[2]Ko CJ, et al. Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis. Oncogene. 2020 Sep;39 (37) :5950-5963.