PPARα/γ agonist 1
PPARα/γ agonist 1 (compound 5b) is a potent and dual PPARα/γ partial agonist with EC50 values of 28 nM and 69 nM for PPARα and PPARγ, respectively. PPARα/γ agonist 1 is a promising prototype for dyslipidemia and diabetes research[1].
Product Specifications
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pparα-γ-agonist-1.html
Concentration
10mM
Purity
99.69
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(OC1=CC=C(C=C1)/C=C/C2=CC=CC=C2)(C(N)=O)C
Molecular Formula
C18H19NO2
Molecular Weight
281.35
References & Citations
[1]Luiz A Dutra, et al. Discovery of (E) -4-styrylphenoxy-propanamide: A dual PPARα/γ partial agonist that regulates high-density lipoprotein-cholesterol levels, modulates adipogenesis, and improves glucose tolerance in diet-induced obese mice. Bioorg Chem. 2022 Mar;120:105600.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARα; PPARγ
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040856-100 1x 100 µL
WT1 (Wilm's Tumor 1) (6F-H2), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNCB3201-500 1x 500 µL
CD137 / 4-1BB / TNFRSF9 (4-1BB/3201), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
![Tau (MAPT) Rabbit Monoclonal Antibody [Clone ID: OTIR10C1]](https://cdn.genprice.uk/products/937/68dd1b74061270361ea1972e/imageurl/ta592889.webp)
TA592889 100 µL
Tau (MAPT) Rabbit Monoclonal Antibody [Clone ID: OTIR10C1]
Sign In for Pricing
View Details 