DNA Gyrase-IN-12
DNA Gyrase-IN-12 (Compound 6d) is a DNA gyrase inhibitor. DNA Gyrase-IN-12 has Antibacterial activity and MIC value of vancomycin-intermediate S. aureus (VISA) and Enterococcus faecalis strains is between 0.031 and 0.0625 μg/mL[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dna-gyrase-in-12.html
Smiles
O=C(N1CCC(NC2=CC(C(N3)=NOC3=O)=CC=C2NC(C4=C(Cl)C(Cl)=C(C)N4)=O)CC1)OC(C)(C)C
Molecular Formula
C24H28Cl2N6O5
Molecular Weight
551.42
References & Citations
[1]Zidar N, et al. Improved N-phenylpyrrolamide inhibitors of DNA gyrase as antibacterial agents for high-priority bacterial strains. Eur J Med Chem. 2024 Nov 15;278:116823.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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