DNA Gyrase-IN-12
DNA Gyrase-IN-12 (Compound 6d) is a DNA gyrase inhibitor. DNA Gyrase-IN-12 has Antibacterial activity and MIC value of vancomycin-intermediate S. aureus (VISA) and Enterococcus faecalis strains is between 0.031 and 0.0625 μg/mL[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dna-gyrase-in-12.html
Smiles
O=C(N1CCC(NC2=CC(C(N3)=NOC3=O)=CC=C2NC(C4=C(Cl)C(Cl)=C(C)N4)=O)CC1)OC(C)(C)C
Molecular Formula
C24H28Cl2N6O5
Molecular Weight
551.42
References & Citations
[1]Zidar N, et al. Improved N-phenylpyrrolamide inhibitors of DNA gyrase as antibacterial agents for high-priority bacterial strains. Eur J Med Chem. 2024 Nov 15;278:116823.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6263506-01 0.1 mL
CA15-3 (Breast Tumor, 15-3, MUC1, MUC-1) (MaxLight 405)
Sign In for Pricing
View Details MBS6263506-02 5x 0.1 mL
CA15-3 (Breast Tumor, 15-3, MUC1, MUC-1) (MaxLight 405)
Sign In for Pricing
View Details MBS6479866-01 0.1 mL
Hemagglutinin Tag (YPYDVPDYA) (HA Tag) (MaxLight 405)
Sign In for Pricing
View Details 
MBS6479866-02 5x 0.1 mL
Hemagglutinin Tag (YPYDVPDYA) (HA Tag) (MaxLight 405)
Sign In for Pricing
View Details 
031232-AP 200 µL
RUVBL1 (RUVBL1, INO80H, NMP238, TIP49, TIP49A, RuvB-like 1, 49kD TATA box-binding protein-interacting protein, 54kD erythrocyte cytosolic protein, INO80 complex subunit H, Nuclear matrix protein 238, Pontin 52, TIP49a, TIP60-associated protein 54-alpha) (AP) discontinued
Sign In for Pricing
View Details