NSD2 ligand 1

12352005

Histone Methyltransferase; Ligands for Target Protein for PROTAC

Reference compound

Epigenetics; PROTAC

Cancer-programmed cell death

Cancer

https://www.medchemexpress.com/nsd2-ligand-1.html

99.76

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

O=C(N1)COC2=C1C=CC(C(N(C3CC3)CC4=CC=C(C(NC5=CC=C(O)C=C5)=O)C=C4)=O)=C2

C26H23N3O5

457.48

[1]Liu L, et al. Discovery of LLC0424 as a Potent and Selective in Vivo NSD2 PROTAC Degrader. J Med Chem. 2024 May 9;67 (9) :6938-6951.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

Reference compound1

No Development Reported