NSD2 ligand 1
Product Specifications
UNSPSC Description
NSD2 ligand 1 is a NSD2 ligand. NSD2 ligand 1 can be used for synthesis of LLC0424 (HY-161574) (a PROTAC NSD2 degrader)[1].
Target Antigen
Histone Methyltransferase; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Epigenetics;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsd2-ligand-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(N1)COC2=C1C=CC(C(N(C3CC3)CC4=CC=C(C(NC5=CC=C(O)C=C5)=O)C=C4)=O)=C2
Molecular Weight
457.48
References & Citations
[1]Liu L, et al. Discovery of LLC0424 as a Potent and Selective in Vivo NSD2 PROTAC Degrader. J Med Chem. 2024 May 9;67(9):6938-6951.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161575/NSD2-ligand-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161575/NSD2-ligand-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
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