Helioxanthin

Helioxanthin (ACH126447) has in vitro antiviral activity with an EC50 of 1 μM against HBV and is also active against flaviviruses.

Product Specifications

CAS Number

18920-47-3

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

HBV; HCV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/helioxanthin.html

Purity

99.76

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1OCC2=C(C3=CC=C(OCO4)C4=C3)C5=C6OCOC6=CC=C5C=C21

Molecular Formula

C20H12O6

Molecular Weight

348.31

Precautions

H315, H319, H335

References & Citations

[1]Yeo H, et al. Synthesis and antiviral activity of helioxanthin analogues. J Med Chem. 2005 Jan 27;48 (2) :534-46.|[2]Cheng, Y. C.; Chou, C. K.; Fu, L.; Kuo, Y. H.; Yeh, S. F.; Zhu, J.;  Zhu, Y. Inhibition and treatment of hepatitis B virus and flavivirus by helioxanthin and its analogues. U.S. Patent  6306899 B1, 2001.|[3]Ying C, et al. Helioxanthin analogue 8-1 inhibits duck hepatitis B virus replication in cell culture. Antivir Chem Chemother. 2010;21 (2) :97-103.