Anti-CHRDL1 monoclonal Antibody
Boster Bio Anti-CHRDL1 monoclonal Antibody catalog # M08014. Tested in WB, ICC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Chordin-like protein 1; Neuralin-1; Neurogenesin-1; Ventroptin; CHRDL1; NRLN1;
Gene Name
CHRDL1
UniProt
Q9BU40
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human CHRDL1.
Clonality
Monoclonal
Tissue Specificity
Expressed in the developing cornea and in the eye anterior segment in addition to the retina. Differentially expressed in the fetal brain. There is high expression in cerebellum and neocortex. Expressed in retinal pericytes.
Applications
WB, ICC
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity) . May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
Molecular Weight
51168 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Chordin-like protein 1
Subcellular Location
Secreted .
Protein Name
Chordin-like protein 1
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