Anti-TBL1 (4H2) monoclonal TBL1X Antibody
Boster Bio Anti-TBL1 (4H2) monoclonal TBL1X Antibody catalog # M07014. Tested in WB, ICC applications. This antibody reacts with Human.
Product Specifications
Synonyms
F-box-like/WD repeat-containing protein TBL1X; SMAP55; Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked; TBL1X; TBL1;
Gene Name
TBL1X
UniProt
O60907
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant human TBL1 protein fragments expressed in E.coli.
Clonality
Monoclonal
Tissue Specificity
Ubiquitous.
Applications
WB, ICC
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units (PubMed:14980219) . Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange (PubMed:21240272) .
Molecular Weight
62496 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
F-box-like/WD repeat-containing protein TBL1X
Subcellular Location
Nucleus . Colocalized with MECP2 to the heterochromatin foci.
Protein Name
F-box-like/WD repeat-containing protein TBL1X
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