Anti-SWAP70 monoclonal Antibody
Boster Bio Anti-SWAP70 monoclonal Antibody catalog # M06972. Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat, Hamster.
Product Specifications
Synonyms
Switch-associated protein 70; SWAP-70; SWAP70; KIAA0640; HSPC321;
Gene Name
SWAP70
UniProt
Q9UH65
Host
Mouse
Reactivity
Human, Mouse, Rat, Hamster
Immunogen
Recombinant full length Human SWAP70.
Clonality
Monoclonal
Tissue Specificity
Expressed only in mature B-cells including those associated with mucosa-associated tissue and bronchus- associated tissue (PubMed:10681448) . Widely expressed. Abundant in spleen, and fairly abundant in kidney, lung and liver. Also found in monocytes and macrophages (PubMed:12925760) .
Applications
WB, IP
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4) -bisphosphate production and cell protrusion (By similarity) .
Molecular Weight
68998 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Switch-associated protein 70
Subcellular Location
Cytoplasm
Protein Name
Switch-associated protein 70
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