Anti-Rad23B (5H1) monoclonal Antibody
Boster Bio Anti-Rad23B (5H1) monoclonal Antibody catalog # M02174. Tested in WB, ICC, IHC applications. This antibody reacts with Human, Mouse, Rat, Monkey.
Product Specifications
Synonyms
UV excision repair protein RAD23 homolog B; HR23B; hHR23B; XP-C repair-complementing complex 58 kDa protein; p58; RAD23B;
Gene Name
RAD23B
UniProt
P54727
Host
Mouse
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Purified recombinant human Rad23B protein fragments expressed in E.coli.
Clonality
Monoclonal
Applications
WB, ICC, IHC
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum- associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome.
Molecular Weight
43171 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
UV excision repair protein RAD23 homolog B
Subcellular Location
Nucleus. Cytoplasm. The intracellular distribution is cell cycle dependent. Localized to the nucleus and the cytoplasm during G1 phase. Nuclear levels decrease during S- phase; upon entering mitosis, relocalizes in the cytoplasm without association with chromatin.
Protein Name
UV excision repair protein RAD23 homolog B
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