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Anti-CD11C (8E3) monoclonal ITGAX Antibody

Boster Bio Anti-CD11C (8E3) monoclonal ITGAX Antibody catalog # M00357-2. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Integrin alpha-X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD11c; ITGAX; CD11C;

Gene Name

ITGAX

UniProt

P20702

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids of Human CD11C

Clonality

Monoclonal

Tissue Specificity

Predominantly expressed in monocytes and granulocytes.

Applications

WB

Purification

The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

Molecular Weight

127829 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Integrin alpha-X

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Integrin alpha-X

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