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Anti-ZAK MAP3K20 Antibody

Boster Bio Anti-ZAK MAP3K20 Antibody catalog # A32464. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Mitogen-activated protein kinase kinase kinase 20

Gene Name

MAP3K20

UniProt

0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human ZAK (NP_598407.1) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed. Isoform 2 is the predominant form in all tissues examined, except for liver, in which isoform 1 is more highly expressed.

Applications

WB, IHC, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2 (PubMed:10924358, PubMed:11836244, PubMed:15342622, PubMed:21224381) . Involved in limb development (PubMed:26755636) .

Molecular Weight

91155 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Mitogen-activated protein kinase kinase kinase 20

Subcellular Location

Cytoplasm

Protein Name

Mitogen-activated protein kinase kinase kinase 20

Frequently Asked Questions

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