Anti-CPSF3L INTS11 Antibody
Boster Bio Anti-CPSF3L INTS11 Antibody catalog # A32417. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Integrator complex subunit 11; Int11;3.1.27.-; Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; Protein related to CPSF subunits of 68 kDa; RC-68; INTS11
Gene Name
INTS11
UniProt
Q5TA45
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human CPSF3L.
Clonality
Polyclonal
Applications
WB, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Catalytic component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267) .
Molecular Weight
67663 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Integrator complex subunit 11
Subcellular Location
Nucleus
Protein Name
Integrator complex subunit 11
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