Anti-FAM96B CIAO2B Antibody
Boster Bio Anti-FAM96B CIAO2B Antibody catalog # A32386. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Cytosolic iron-sulfur assembly component 2B ; MSS19-interacting protein of 18 kDa; Mitotic spindle-associated MMXD complex subunit MIP18; Protein FAM96B; CIAO2B
Gene Name
CIAO2B
UniProt
Q9Y3D0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human FAM96B (NP_057146.1) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004, PubMed:22678362, PubMed:22678361) . As a CIA complex component and in collaboration with CIAO1 and MMS19, binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins (PubMed:23891004) . As part of the mitotic spindle- associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD (PubMed:20797633) .
Molecular Weight
17663 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Cytosolic iron-sulfur assembly component 2B
Subcellular Location
Nucleus
Protein Name
Cytosolic iron-sulfur assembly component 2B
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