Anti-MINA53 RIOX2 Antibody
Boster Bio Anti-MINA53 RIOX2 Antibody catalog # A32122-2. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Ribosomal oxygenase 2
Gene Name
RIOX2
UniProt
Q8IUF8
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Expressed in liver, skeletal muscle, heart, pancreas, and placenta. Not detected in brain, lung or kidney. Expressed in several lung cancer tissues, but is barely detected in the adjacent non-cancerous tissues. Also highly expressed in several esophageal squamous cell carcinoma (ESCC), and colon cancer tissues, and in various cancer cell lines.
Applications
WB, ICC, IF
Purification
ProA affinity purified
Form
Liquid
Function
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
Molecular Weight
52800 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Ribosomal oxygenase 2
Subcellular Location
Nucleus
Protein Name
Ribosomal oxygenase 2
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