Anti-PAPD7 TENT4A Antibody
Boster Bio Anti-PAPD7 TENT4A Antibody catalog # A32111. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Catalytic subunit of a TRAMP-like complex which has a poly (A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo (A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation.
Synonyms
Non-canonical poly (A) RNA polymerase PAPD7 ;2.7.7.19; DNA polymerase sigma; LAK-1; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; Terminal nucleotidyltransferase 4A
Gene Name
TENT4A
UniProt
Q5XG87
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PAPD7 (NP_008930.1) .
Clonality
Polyclonal
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Catalytic subunit of a TRAMP-like complex which has a poly (A) RNA polymerase activity and is involved in a post- transcriptional quality control mechanism. Polyadenylation with short oligo (A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation.
Molecular Weight
82360 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Non-canonical poly (A) RNA polymerase PAPD7
Subcellular Location
Cytoplasm
Protein Name
Non-canonical poly (A) RNA polymerase PAPD7
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