Anti-PAPD7 TENT4A Antibody

Catalytic subunit of a TRAMP-like complex which has a poly (A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo (A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation.

Non-canonical poly (A) RNA polymerase PAPD7 ;2.7.7.19; DNA polymerase sigma; LAK-1; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; Terminal nucleotidyltransferase 4A

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Catalytic subunit of a TRAMP-like complex which has a poly (A) RNA polymerase activity and is involved in a post- transcriptional quality control mechanism. Polyadenylation with short oligo (A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation.