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Anti-FNDC4 Antibody

Boster Bio Anti-FNDC4 Antibody catalog # A15549. Tested in WB applications. This antibody reacts with Mouse, Rat.

Product Specifications

Synonyms

Fibronectin type III domain-containing protein 4; Fibronectin type III repeat-containing protein 1; FNDC4; FRCP1; UNQ6389/PRO21134;

Gene Name

FNDC4

UniProt

Q9H6D8

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Recombinant protein of human FNDC4

Clonality

Polyclonal

Tissue Specificity

Up-regulated in colon cells of patients with inflammatory bowel disease (IBD) .

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro- inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.

Molecular Weight

25159 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A15549

Product MSDS

https://www.bosterbio.com/msds?sku=A15549

Other Gene Names

Fibronectin type III domain-containing protein 4

Subcellular Location

Membrane ; Single-pass type I membrane protein . Secreted

Protein Name

Fibronectin type III domain-containing protein 4

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