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Anti-Integrator complex subunit 2 INTS2 Antibody

Boster Bio Anti-Integrator complex subunit 2 INTS2 Antibody catalog # A15434. Tested in IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Integrator complex subunit 2; Int2; INTS2; KIAA1287;

Gene Name

INTS2

UniProt

Q9H0H0

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide, corresponding to amino acids 50-100 of Human INTS2.

Clonality

Polyclonal

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

IHC: 1:50-1:200

Form

Liquid

Function

Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable) . Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267) .

Molecular Weight

134323 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A15434

Product MSDS

https://www.bosterbio.com/msds?sku=A15434

Other Gene Names

Integrator complex subunit 2

Subcellular Location

Nucleus membrane

Protein Name

Integrator complex subunit 2

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