Anti-Integrator complex subunit 2 INTS2 Antibody
Boster Bio Anti-Integrator complex subunit 2 INTS2 Antibody catalog # A15434. Tested in IHC applications. This antibody reacts with Human.
Product Specifications
Synonyms
Integrator complex subunit 2; Int2; INTS2; KIAA1287;
Gene Name
INTS2
UniProt
Q9H0H0
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to amino acids 50-100 of Human INTS2.
Clonality
Polyclonal
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
IHC: 1:50-1:200
Form
Liquid
Function
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable) . Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267) .
Molecular Weight
134323 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Integrator complex subunit 2
Subcellular Location
Nucleus membrane
Protein Name
Integrator complex subunit 2
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