Anti-Integrator complex subunit 2 INTS2 Antibody

Boster Bio Anti-Integrator complex subunit 2 INTS2 Antibody catalog # A15434. Tested in IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Integrator complex subunit 2; Int2; INTS2; KIAA1287;

Gene Name

INTS2

UniProt

Q9H0H0

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide, corresponding to amino acids 50-100 of Human INTS2.

Clonality

Polyclonal

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

IHC: 1:50-1:200

Form

Liquid

Function

Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable) . Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267) .