Anti-ETAA1 Antibody
Boster Bio Anti-ETAA1 Antibody catalog # A14604. Tested in WB applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
Ewing's tumor-associated antigen 1
Gene Name
ETAA1
UniProt
Q9NY74
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A synthetic peptide corresponding to residues in Human ETAA1.
Clonality
Polyclonal
Tissue Specificity
Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity (PubMed:27601467, PubMed:27723720, PubMed:27723717) . Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 (PubMed:27723720, PubMed:27723717) . Probably only regulates a subset of ATR targets (PubMed:27723720, PubMed:27723717) .
Molecular Weight
103440 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Ewing's tumor-associated antigen 1
Subcellular Location
Nucleus
Protein Name
Ewing's tumor-associated antigen 1
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