Anti-F-box/LRR-repeat protein 12 FBXL12 Antibody
Boster Bio Anti-F-box/LRR-repeat protein 12 FBXL12 Antibody catalog # A13439. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
F-box/LRR-repeat protein 12; F-box and leucine-rich repeat protein 12; F-box protein FBL12; FBXL12; FBL12;
Gene Name
FBXL12
UniProt
Q9NXK8
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human FBXL12 (NP_060173.1) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein) -type E3 ubiquitin ligase complex. Mediates the polyubiquitination and proteasomal degradation of CAMK1 leading to disruption of cyclin D1/CDK4 complex assembly which results in G1 cell cycle arrest in lung epithelia.
Molecular Weight
37026 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
F-box/LRR-repeat protein 12
Protein Name
F-box/LRR-repeat protein 12
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