Anti-G-protein coupled receptor 52 GPR52 Antibody
Boster Bio Anti-G-protein coupled receptor 52 GPR52 Antibody catalog # A13015-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
G-protein coupled receptor 52
Gene Name
GPR52
UniProt
Q9Y2T5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding Human GPR52.
Clonality
Polyclonal
Tissue Specificity
Expressed in brain, especially in striatum.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241) . May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241) . Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228) .
Molecular Weight
41354 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
G-protein coupled receptor 52
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Name
G-protein coupled receptor 52
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