Anti-ASCC2 Antibody

Boster Bio Anti-ASCC2 Antibody catalog # A12860. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Activating signal cointegrator 1 complex subunit 2; ASC-1 complex subunit p100

Gene Name

ASCC2

UniProt

Q9H1I8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human ASCC2 (NP_115580.2) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains (PubMed:29144457) . Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347) .