Anti-Integrator complex subunit 10 INTS10 Antibody

Boster Bio Anti-Integrator complex subunit 10 INTS10 Antibody catalog # A12735. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Integrator complex subunit 10; Int10; INTS10; C8orf35;

Gene Name

INTS10

UniProt

Q9NVR2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human INTS10 (NP_060612.2) .

Clonality

Polyclonal

Applications

WB, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable) . May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex (PubMed:23904267) .