Anti-U2AF1L4 Antibody
Boster Bio Anti-U2AF1L4 Antibody catalog # A11846. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Splicing factor U2AF 26 kDa subunit; U2 auxiliary factor 26; U2 small nuclear RNA auxiliary factor 1-like protein 4; U2AF1-like 4
Gene Name
U2AF1L4
UniProt
Q8WU68
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human U2AF1L4 (NP_659424.2) .
Clonality
Polyclonal
Tissue Specificity
Isoform 2 is widely expressed. Isoform 3 is highly expressed in heart, brain and lung, lower expressed in thymus and much lower expressed in peripheral blood leukocytes.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity) . Shows a preference for AGC or AGA (By similarity) .
Molecular Weight
25744 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Splicing factor U2AF 26 kDa subunit
Subcellular Location
Nucleus
Protein Name
Splicing factor U2AF 26 kDa subunit
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