Anti-Chromobox protein homolog 6 CBX6 Antibody
Boster Bio Anti-Chromobox protein homolog 6 CBX6 Antibody catalog # A11651-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Chromobox protein homolog 6; CBX6;
Gene Name
CBX6
UniProt
O95503
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CBX6 (NP_055107.3) .
Clonality
Polyclonal
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530) . PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235) . Recruitment to chromatin might occur in an H3K27me3-independent fashion (By similarity) . May have a PRC1-independent function in embryonic stem cells (By similarity) .
Molecular Weight
43898 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A11651-1
Product MSDS
https://www.bosterbio.com/msds?sku=A11651-1
Other Gene Names
Chromobox protein homolog 6
Subcellular Location
Nucleus
Protein Name
Chromobox protein homolog 6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
